Clean Room Equipment

Marya: Your Professional Clean Room Equipment Manufacturer!

 

Shanghai Marya Pharmaceutical Engineering and Project Co., Ltd. founded in 2014 in Shanghai, China, is a total solution provider specializing in engineering design, clean room engineering, pharmaceutical engineering, pharmaceutical equipment, project management and verification, and other technical services.

About Marya

Engineering design team with more than 20 years of experience

Engineering Design

Our experienced engineering team with more than 20 years experience in cleanroom design and construction can ensure that process and materials for your plant is designed and manufactured in the most cost-effective manner with reliablequality to fulfil GMP/FDA/ISO/SGS requirement.

01

Procurement

Maryas’ 3 manufacturing plants for cleanroom projects are all under strict quality management systems certified to ISO9001 with a focus on continuous quality improvement.

02

Construction

Experienced, professional, high-efficiency and strictly stick to the schedule, our installation engineers and workers team have successfully installed more than 300 projects in 51 countries with high customer satisfaction.

03

Service

The R&D and design personnel are composed of experienced senior engineers and technicians Using advanced production and testing equipment with high accuracy.

04

Quality Control

Adhere to the philosophy of “customer-centric”, Marya creates the ultimate service experience with the heart of the craftsman! We are always on the way to create more value for customers.

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  • HEPA Filter
    The high efficiency particulate air (HEPA) filter is mainly used to capture dust particles and various suspended matters above 0.5μm. The air purifier is mainly composed of a filter element and a...
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  • Clean Room Air Shower
    An air shower is designed to function as a sort of gateway controller between your cleanroom and the rest of the world.
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  • Clean Bench
    A clean bench is an enclosed laboratory bench that is designed to prevent pollution and contamination by controlling and keeping the air cleanliness level at a certain point. It is a type of...
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  • Cleanroom Biosafety Cabinet
    The biological safety cabinet is one type of biocontainment equipment used to provide safety protection for operators through the formation of directional airflows (inflow and downward airflow)....
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  • Glove Leak Detector
    The glove leak detector is a specialized instrument used to test the integrity of oversleeve or gloves of isolator or RABS system or one-piece gloves. The test plate and frame are made of...
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  • VHP Passbox
    VHP Pass box is used for automatic sterilization during transfer, with energy saving and high efficiency as its core. It integrates microbe control and cross-contamination prevention throughout...
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  • Biosafety Cabinet
    The biological safety cabinet is a negative pressure filter exhaust cabinet designed to provide protection for the operator, laboratory environment, and experimental materials (such as primary...
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  • Clean Bench
    The clean bench is a box-type air purification facility that can not only provide a local dust-free clean、operating environment with a cleanliness class of 100 (ISO Class 5) [1], but also enable...
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  • Clean Room Washing Sink
    The stainless steel clean room washing sink is widely used in operating rooms, aseptic rooms, laboratories and other places with high sanitary requirements.
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  • Clean Room Pass Box
    As an auxiliary equipment of clean room, the clean room pass box is mainly used for the transfer of small items between clean area and clean area, non-clean area and clean area
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  • VHP Pass Box
    VHP pass box is mainly used for biological decontamination of the outer surface of the material to avoid the material from the no-level area or low-level area into the high-level area to bring in...
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  • Clean Room Air Shower
    Definition of clean room air shower: It is a kind of local purification equipment with strong versatility in which people or goods enter the clean area by the fan through the air shower nozzle...
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Clean Room Equipment

 

Definition of Clean Room Equipment

The effectiveness of a cleanroom is dependent on the types of equipment used to complete assemblies, testing, and research. As with all of the materials used in a cleanroom, clean room equipment must meet the rigorous standards for cleanrooms to maintain its ISO classification. Cleanrooms require the highest degree of sanitization; these high standards apply to every item that enters the room, from a pad of paper to large, hooded air circulation systems. Much like any work environment, cleanrooms have necessary work materials. The uniqueness of clean room equipment is its extraordinary cleanliness.

 

 
 
Advantages of Clean Room Equipment You Want to Know

 

Using the right cleanroom equipment is essential for any cleanroom operation. Not only does it help maintain a sterile environment, but it also provides many other benefits. These include

 

01.

Increased Productivity

Using cleanroom equipment allows personnel to work more efficiently and effectively, resulting in increased productivity.

02.

Improved Quality

Using the right cleanroom equipment helps to improve product quality, as it reduces the risk of contamination and ensures that processes are performed correctly.

03.

Cost Savings

Using cleanroom equipment can help save money in the long run, reducing the need for costly repairs and replacements due to contamination or other issues.

04.

Compliance

Using the right cleanroom equipment helps to ensure compliance with industry standards and regulations, which is essential for any cleanroom operation.

 

 
Types of Clean Room Equipment
 

 

Cleanroom Air Shower

A cleanroom air shower serves as a gateway control between the outside environment and the uncontaminated cleanroom enclosure. It is installed as part of the entryway as a means of reducing the introduction of contaminant matter. Though all cleanroom personnel are required to wear proper apparel, there is still the potential of the introduction of lint, small fragments, or debris into the cleanroom. The air shower removes such potentially hazardous elements. The cleanroom air shower is a self-contained chamber that has high velocity air flow and low pressure. When a person enters through one of the dual locking doors, a high velocity fan blows air over them. The air entering the chamber is HEPA filtered and air washes the occupant of particulate matter that moves to the low pressure side of the chamber.

Lab Oven

Laboratory ovens have a uniform construction consisting of an enclosed insulated space with a heating element. There are a wide variety of designs with specialized types for thermal processing and types for curing and testing. Laboratory ovens are divided according to their heating method. The types of lab ovens include forced air, gravity convection, and mechanical. Of the three types, mechanical ovens are most commonly used. Forced air ovens use mounted blowers that circulate high velocity air. The blowers protect batches and enhance heat transmission. Gravity ovens do not have circulation fans or blowers. They pass heat through convection. Mechanical ovens have blowers or fans and have better temperature uniformity.

Cleanroom Door Swing

Cleanroom door swings can be single or double and are designed to maintain the particle free sterile environment. They provide exceptional security, provide protection against contamination, and are the first line of defense for the cleanroom's integrity. As every other component of a cleanroom, door swings are required to meet a set of cleanliness specifications. More and more cleanrooms are beginning to use automatic door swings that allow for greater control of the door, such as the speed at which the door opens and closes as well as obstruction sensing devices. Depending on the ISO classification of the cleanroom, it may have a double swing door entry with a pass thru.

Cleanroom Filters

Specialty filters used in lab or cleanroom environments ro remove particles or fumes. Filter types include: prefilters, HEPA, ULPA, acid gas, activated charcoal, ammonia gas, formaldehyde, mercury and radioactive iodine.

Nitrogen Generator

A nitrogen generator performs a process called pressure swing adsorption and membrane technology, which is the extraction of nitrogen from the air followed by its compression. It provides a pure flow of nitrogen without the need for canisters. Nitrogen generators provide 99% pure nitrogen at medical grade levels to desiccator cabinets, gloveboxes, and vacuum chambers, to name a few applications.

Desiccator Cabinet or Dry Box

A desiccator is a laboratory instrument. It is a round closed container made of exceptionally durable glass used for storage of items that require a moisture free environment. At the bottom of the desiccator is a perforated plate that is located above the drying agent, which can be anhydrous calcium chloride, calcium sulphate, or silica. The four types of desiccators are standard, vacuum, automatic, and gas purge. Standard models are used as desiccator cartridges and are economical. Vacuum types use a pump to remove moisture. Automatic models operate continuously using a fan and heater. Gas purge models use nitrogen and argon as atmospheric drying agents.

Vacuum Chamber

The purpose of a vacuum chamber is to create a pressure and air free environment for the purpose of testing components. It is a rigid and well controlled environment that comes in several different configurations to meet the needs for testing specific materials. Vacuum chambers can be used for batch testing and processing applications that necessitate a sustained and precision regulated level of vacuum. Depending on the testing needs, vacuum chambers can be made of acrylic, aluminum, or stainless steel. The materials of the chamber determine the level of testing it can perform.

Biosafety Cabinet

Another specialized fume hood form is a biosafety cabinet, which is a specially designed enclosure for the handling of contaminated materials or pathogens that necessitate observation in a defined biologically safe space. Biosafety cabinets use vertical laminar air flow in order to form a barrier against contaminants. There are three classes of biosafety cabinets, Classes I,II, and III, with class three being the most stringent and capable of handling highly contagious microbiological agents.

Laminar Flow Hood

A specialized type of fume hood is a laminar flow hood that separates the air flow into layers to cleanse it of contaminants. Much like other fume hoods, a laminar flow hood is an enclosed work space with the added feature of protecting samples from airborne contaminants to create a dust free environment to minimize contaminants. A laminar flow hood has a filter pad, fan, and HEPA filter. The fan pulls the ambient air into the HEPA filtration system from which it is passed to the work space. The two types of laminar flow hoods are horizontal and vertical air flow systems with the horizontal flow system having a back to front flow and the vertical system having a downward flow.
Vertical air flow laminar hoods direct the flow downward and reinforces the effects of gravity by sweeping particles down and out of the enclosure. They are used when floor space is at a premium and eliminate contaminants from floating around inside the enclosure.
With a horizontal laminar flow hood, air flows through a HEPA filter and is forced across the work surface from back to front. They have a deeper style to make room for the rear mounted filter and fan unit and require additional clearance.

Fume Hoods

Fume hoods, known as fume chambers and cupboards, are venting systems that capture and contain toxic fumes, particulate matter, and vapors. There are several types of fume hoods, including PVC ducted, carbon filter recirculating, laminar air flow, biosafety cabinets, clean benches, and snorkel exhausts. The primary functions of fume hoods are to protect the user, the product, and the environment. The use of cleanroom fume hoods is essential in cleanroom environments where noxious chemicals and hazardous materials are tested and researched.

 
Tips for Choosing the Right Clean Room Equipment

 

When choosing the right cleanroom equipment, there are a few things to keep in mind. Here are some tips for selecting the right cleanroom equipment for your needs

Research

Do your research and find out what types of cleanroom equipment are available and which ones are best suited for your particular cleanroom.

Quality

Make sure to choose cleanroom equipment that is of high quality and designed to meet the requirements of your cleanroom.

Certification

Look for cleanroom equipment certified by an independent organization, as this will ensure that it meets industry standards and regulations.

Budget

Make sure to factor in your budget when choosing cleanroom equipment, as many different price points are available.

 

 
Clean Room Equipment Maintenance
 

Clean room equipment plays a crucial role in maintaining controlled environments for various industries such as semiconductor manufacturing, pharmaceuticals, and healthcare. Proper maintenance is essential to ensure the equipment functions effectively and complies with the required cleanliness standards. Here are key steps for maintaining clean room equipment

01/

Regular Inspections

Conduct routine visual inspections to identify any signs of wear, damage, or contamination. Check for loose or damaged components and ensure proper alignment.

02/

Cleaning Procedures

Follow manufacturer guidelines for cleaning procedures. Use recommended cleaning agents and methods to avoid introducing contaminants. Establish a regular cleaning schedule to prevent particle build-up.

03/

Calibration

Schedule regular calibration of sensors and monitoring devices. Ensure that instruments measuring temperature, humidity, and particle counts are accurate. Keep calibration records for auditing purposes.

04/

Filter Replacement

Regularly replace filters according to the specified schedule. Verify that replacement filters meet the required cleanliness standards. Document filter replacement dates for reference.

05/

HVAC System Maintenance

Maintain the heating, ventilation, and air conditioning (HVAC) systems to ensure proper air circulation. Clean ducts, coils, and vents regularly to prevent the spread of contaminants. Monitor and adjust airflow as needed.

06/

Seal Integrity

Inspect seals and gaskets regularly to ensure a tight seal on doors and access points. Replace damaged seals promptly to prevent air leaks and contamination.

 

Certifications

 

Shanghai Marya has received the CE, HTT, Quality Management System, and SGS certificates.

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Our Factory
 

 

We have three manufacturing bases, covering a total area of about 30000 square meters, including the production of main cleanroom materials and pharmaceutical equipment.

 

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Video Display
 

 

 

 
Ultimate FAQ Guide to Clean Room Equipment
 

 

Q: How to care for clean room equipment?

A: To ensure the longevity and efficiency of cleanroom equipment, it is important to perform regular maintenance and care. This includes cleaning and sanitizing the equipment regularly, ensuring all parts are in working order, and replacing any worn or damaged parts as needed. Additionally, it is crucial to follow the manufacturer's instructions for the maintenance and care of the equipment.

Q: What is a fume hood in the context of clean rooms?

A: A fume hood in a clean room context is a ventilated enclosure that protects personnel from hazardous fumes or chemicals while working with materials that could potentially contaminate the clean room environment.

Q: What are ISO standards for clean rooms?

A: ISO standards provide guidelines and requirements for the design, construction, operation, and monitoring of clean rooms to ensure consistent performance and cleanliness levels.

Q: How are clean room equipment and supplies stored?

A: Clean room equipment and supplies are stored in designated areas within the clean room or adjacent anterooms, following protocols to prevent contamination and maintain cleanliness.

Q: What is a clean room airlock?

A: A clean room airlock is a controlled entry and exit chamber with interlocking doors that allow personnel and materials to transition between different cleanliness zones without compromising the integrity of the clean room.

Q: How do clean rooms control humidity?

A: Clean rooms control humidity through the use of HVAC systems equipped with dehumidifiers and humidifiers, maintaining optimal levels to prevent condensation and microbial growth.

Q: How do clean rooms handle waste disposal?

A: Clean rooms have specific protocols and equipment for waste disposal, including sealed containers, vacuum systems, and decontamination processes, to ensure the safe removal of contaminants without reintroducing them into the environment.

Q: What is the role of clean room monitoring systems?

A: Clean room monitoring systems continuously monitor parameters such as particle counts, temperature, humidity, and pressure to provide real-time data and alerts for maintaining compliance and identifying potential issues.

Q: How do clean rooms work?

A: Clean rooms operate by maintaining a controlled environment with low levels of pollutants such as dust, microbes, and aerosol particles. They use specialized equipment to filter air, control temperature, and regulate humidity.

Q: What is a HEPA filter?

A: A HEPA (High-Efficiency Particulate Air) filter is a type of air filter capable of capturing 99.97% of particles that are 0.3 microns in diameter or larger.

Q: What is a laminar flow hood?

A: A laminar flow hood is a device that directs filtered air downward in a vertical or horizontal flow to create a clean work environment for tasks such as assembling delicate components.

Q: What is an air shower?

A: An air shower is a chamber that personnel must pass through before entering a clean room. It blows high-velocity, filtered air to remove contaminants from clothing and equipment.

Q: How are clean rooms classified?

A: Clean rooms are classified based on the number and size of particles allowed per cubic meter of air, often ranging from ISO Class 1 to ISO Class 9, with ISO Class 1 being the most stringent.

Q: How do clean room gloves differ from regular gloves?

A: Clean room gloves are specially designed to minimize particulate generation and are often made from materials like nitrile or latex that undergo stringent cleaning processes.

Q: What is a pass-through chamber?

A: A pass-through chamber is a controlled access point that allows materials to be transferred into and out of the clean room without compromising its cleanliness.

Q: How are clean room equipment and tools sterilized?

A: Clean room equipment and tools are typically sterilized using methods such as autoclaving, gamma irradiation, or chemical disinfection, depending on the application and material compatibility.

Q: What is a clean bench?

A: A clean bench is a type of workbench with a built-in laminar flow hood that provides a localized clean air environment for specific tasks.

Q: How often should clean room equipment be inspected and maintained?

A: Clean room equipment should be inspected and maintained regularly according to a scheduled preventive maintenance program to ensure optimal performance and compliance with standards.

Q: What are the types of cleanroom filters?

A: HEPA Filter For Cleanrooms: A High Efficiency Particulate Air (HEPA) is an air filter.  The filter must remove 99.97% o f particles with a size of 0.3 micron or larger.
ULPA Filter: An Ultra Low Particulate Air (ULPA) Filter removes 99.999% of particles 0.12 micron or larger.
Cleanroom Filters: Specialty filters used in lab or cleanroom environments ro remove particles or fumes. Filter types include: prefilters, HEPA, ULPA, acid gas, activated charcoal, ammonia gas, formaldehyde, mercury and radioactive iodine.
Fan Filter Unit or FFU: A fan attached to a 2'x2' or 2'x4' sheet metal frame containing a HEPA or ULPA filter. Used in a wide variety of laboratories applications and clean room ceilings. The filter has a top side prefilter and protective screen over the filter.
Motorized HEPA Filter or MCF: Another name for the Fan Filter Unit, FFU or Motorized Ceiling Filter 
HEPA Filter Module: A self contained High Efficiency Particulate Air Filter (HEPA) fan filter unit used in a ceiling or over the top of equipment to create a cleanroom environment. The filter module is also available with an air duct collar and no fan.
Terminal HEPA Filter: Designed to provide HEPA or ULPA filtered air from a tee-bar ceiling. Standard filters are available 2'x2' or 2'x4' with a 10” diameter collar.  The collars are connected to a duct which is supplied air from a large central blower.
Ceiling HEPA Filter Air Conditioning  Unit: A fully integrated modular environmental system specifically designed and manufactured for the general cleanroom industry. A motorized HEPA filter is mounted directly into the unit which controls temperature and humidity. Available in ½ to, 1 and 2 ton configurations. The multi-panel design allows for variable duct connections making it ideal for plenum, once-through and re-circulating installations used in softwall cleanrooms, upgrades, problematic areas, additions, spot cooling, and process isolator applications.

Q: What are the types of laminar flow clean bench?

A: Laminar Flow Clean Bench: Another name for a Laminar Flow Hood
Horizontal Laminar Flow Hood: HEPA or ULPA filters are at the back of the cabinet and flow across the work area toward the operator. Hoods are available with an attached table or without a table. When vibration is a concern the laminar flow hood should have a table which is not attached or the motor/blower vibration will transfer to the work surface.
Vertical Laminar Flow Hood: HEPA or ULPA filters are above the work area and flow down toward the work space. Hoods are designed in a number of styles to meet a wide range of requirements:
Mode “O” Open = Open Base no table
Mode “WO” Wash Out = Attached solid table
Mode “WT” Wash Thru = Attached perforated table
Mode “ER” Exhaust Recirculated = A portion of the air is exhausted out the back and also recirculated
Mode “E” Exhaust = All of the air is exhausted out the back
Economical Horizontal Laminar Flow Hood: The HEPA filter has a simple enclosure with acrylic side shields and top. The cabinet sits on a standard table.
Portable Laminar Flow Hood: The hood has casters attached to the base for easy mobility.
Stainless Steel Laminar Flow Hood: Body of the laminar flow hood is made of stainless steel which allows the cabinet to be wiped down with a sterile disinfectant.
Economical Laminar Flow Hood: HEPA filter has a painted steel shroud which sits on standard Metro Wire posts and shelves. Vinyl is attached to the shroud to enclose the hood and provide a ISO 5 or Class 100 work station.

We're well-known as one of the leading clean room equipment manufacturers and suppliers in China. Please feel free to buy high quality clean room equipment made in China here from our factory. For more information, contact us now.

VHP Generator, Cleanroom System, Stability Test Chamber