Vials are divided into molded and tube-type according to the process. The tube-type bottle is first drawn into a glass tube, and then made into a bottle with the glass tube in a vertical turntable machine. The molded bottle is made of borax and quartz sand in a kiln line machine. The tube-type bottle does not use a mold, but only two sets of mold wheels are used. While a complete set of molds are required for the molded bottle. The appearance of the tube-type bottle looks brighter. The transparency is better, while the molded bottle is rougher. The molded bottle is mainly made of soda-lime glass, which has poor physical and chemical stability, and is mostly used to hold veterinary drugs. The material of the tube-type bottle is mostly borosilicate glass, including low borosilicate glass and neutral borosilicate glass. The cost of neutral borosilicate is relatively high, and the raw material glass tube is basically imported, which its popularity rate is very low in China. It is mostly used to store high value-added drugs such as blood serum and freeze-dried powder injection. Low-borosilicate vials can account for more than 95% of the domestic market share, and the popularity rate is particularly high.
The tube-type bottle has stable chemical properties, uniform wall thickness, good heat transfer and transparency. Mainly used for the packaging of vaccines, biological preparations, powder injections, freeze-dried drugs and cosmetics.
Vials are generally brown or transparent:
Brown vials: some substances sensitive to light, which are sensitive to light with higher energy (shorter wavelength), such as light in blue ~ purple band, but not sensitive to red light with low energy. It is necessary to filter out the light in the middle wavelength band of visible light to avoid the decomposition of drugs in light. Brown vial is made of low borosilicate glass, and its manufacturing method is piping. Brown vial mouth can be equipped with threaded plastic cap, butyl gasket, silica gel gasket, PE gasket, etc. to improve the tightness of the bottle. Piping glass bottles generally have rigid signs, which are also made of mold shapes. It can be customized according to customers’ needs, or the bottle body can be printed with printing and labeling techniques, such as company name, design, advertising language, product name, product description, etc. according to different requirements of customers. Printed vial is made of high borosilicate glass, which has high transparency and good chemical stability.
Transparent vial: quartz sand is the main raw material, and other auxiliary materials are melted into liquid at high temperature. Then the essential oil bottle is injected into the mold, cooled, cut and tempered to form a glass bottle. It has small linear expansion coefficient, small dispersion, good chemical stability, high thermal stability and good electrical insulation. Using this kind of glass bottle as the packaging of oral liquid can make the oral liquid look different, and it can be equipped with aluminum cover, butyl gasket, silica gel gasket, etc.
Difference from ampoules:
1. Appearance: Ampoules belong to the slender bottle, while vials have a relatively flat bottle mouth, thin neck, uniform thickness below the neck, slightly thicker than the neck and slightly thinner than the bottle body. It is generally used for the packaging of vaccines, biological agents, powder injections, freeze-drying and other medicines.
2. Different storage supplies: Vials are generally used to store powder and granular items, which are more stable than ampoules.
3. Bottle mouth is different: Ampoules are fully sealed package. When using, the bottle mouth should be broken, while the bottle mouth of vials has a rubber stopper.
Vial capping machine:
1. Vial capping machine is equipped with multiple capping heads, which can be selected according to the size of different bottle caps. The bottle capping head can be selected by the vial before official use.
2. If the cover is not rolled tightly, you can unscrew lock nut of capping head and roll the upper capping head counterclockwise, then lock the upper fixing nut.
3. When the cap is tightly pressed with the capping head, the three capping cutter heads that keep rotating rotate for several times to tighten the bottle cap. (The motor must run clockwise.)
4. Push the handle forward to make the rolled cap return to its original position with the tray, and the whole operation process is completed. Repeat the above operation every time when a bottle cap is rolled.
Vial washing machine:
With the increase of laboratory labor cost and the improvement of testing requirements, more and more scientific research workers choose automatic bottle washing machine. Laboratory cleaning is becoming more standardized, automatic and intelligent. The popularization of bottle washing machine is a general trend.
The working principle of vial washing machine is mainly to convert the high-frequency oscillating electric energy generated by ultrasonic electric energy into mechanical energy, which is emitted into the cleaning medium in the tank to produce cavitation effect. Bubbles peel off the sundries on the surface of the bottle body quickly, thus achieving the purpose of thoroughly cleaning the inner and outer walls of the bottle. Automatic vial washing machine is mainly composed of transmission part, cleaning tank part, water circulation part, electrical appliances and so on. In the transmission part, the motor, deceleration motor, pulley, gear, sprocket, etc. complete the transportation of the bottle. The cleaning water tank is assisted by ultrasonic wave generator and the large and small water tanks to complete cleaning work. The water circulation part is supplied by water pumps, inlet and outlet pipes, etc. to complete the water supply required by the ultrasonic generator. The electrical part is controlled by the motor frequency conversion control part and the ultrasonic generator control part to complete the continuous cleaning of the machine.