What is Ampoule Filling And Sealing Machine
Automatic Ampoule Filling & Sealing Machine is compact & versatile machine for the filling & sealing of glass ampoules. Ampoule Filling Sealing Machine uses in the pharmaceutical industry, apart from this Ampoule Filling Sealing Machine also having application in industries like biotech, cosmetic & chemicals. Machine perform filling and closing operation on pharmaceutical glass ampoules ranging from 1ml to 30ml.
High-efficiency filling and sealing
The ampoule filling and sealing machine employs automated control systems to achieve high-speed filling and sealing, enhancing production efficiency.
Precision and reliability
The machine ensures accurate dosage of medication for each ampoule and provides secure and reliable sealing to prevent leakage and contamination.
Versatility
Ampoule filling and sealing machines can accommodate various sizes and types of ampoules, allowing for easy adjustment of filling and sealing parameters to meet the requirements of different drugs.
Automated operation
Modern ampoule filling and sealing machines are equipped with intelligent control panels and touch screens for user-friendly operation. Operators can set filling and sealing parameters and monitor the entire process, ensuring safety and stability in production.
Cartridge Filling Production Line
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Prefilled Syringe Filling Stoppering Machine
Prefilled syringe filling stoppering machine is a modern piece of equipment that is designed to accurately and consistently fill syringes with a range of pharmaceutical and medical products. This includes liquid solutions, suspensions, and even viscous materials of different types.
Vial Washing Filling Stoppering Capping Line
We offer a range of vial filling lines for the pharmaceutical industry, including vial washing filling capping lines, and vial washing filling stoppering capping lines. Our machines are designed to meet the GMP standards and ensure the highest quality of pharmaceutical packaging.
Sterile Vial Liquid Filling Machine
Vial filling machine is a highly efficient and automated device that is used to fill and seal vials with liquids or semi-solids, such as vaccines, medicines, and other injectable drugs. These machines are designed to increase the speed and accuracy of vial filling and sealing, and are widely used in the pharmaceutical, biotech, and cosmetic industries.
Sterile Prefilled Syringe Filling Machine
Vial filling machine is a highly efficient and automated device that is used to fill and seal vials with liquids or semi-solids, such as vaccines, medicines, and other injectable drugs. These machines are designed to increase the speed and accuracy of vial filling and sealing, and are widely used in the pharmaceutical, biotech, and cosmetic industries.
BFS three-in-one technology of BFS machine refers to the automatic process of completing blowing, filling and sealing operation successively in single equipment; it is mainly used for aseptic packaging of plastic containers of liquid filling products in pharmaceutical, chemical and food industries, etc.
The syrup filling line is a production line composed of bottle loading machine or bottle unscrambling machine, filling and cap screwing machine, aluminum foil sealing machine, adhesive sticker labeling machine, etc.
The oral liquid filling machine is composed of vertical ultrasonic bottle washing machine, drying sterilizing machine and filling capping machine. All those three single machines can work together as a unit, or be used separately.
The ampoule washing drying filling sealing production line is composed of vertical ultrasonic bottle washing machine, hot air circulating sterilizing tunnel oven and vertical filling and sealing machine.
Why Choose Us
Competitive pricing
We offer competitive pricing for our services without compromising on quality. Our prices are transparent, and we do not believe in hidden charges or fees.
Quality assurance
We have a rigorous quality assurance process in place to ensure that all our services meet the highest standards of quality. Our team of quality analysts checks each project thoroughly before it is delivered to the client.
Expertise and experience
Our team of experts have years of experience in delivering high quality services to our clients. We hire only the best professionals who have a proven track record of delivering exceptional results.
State-of-the-art technology
We use the latest technology and tools to deliver high quality services. Our team is well-versed in the and advancements in technology and uses them to provide the best results.
One-stop service
We promise to provide you with the fastest reply, the best price, the best quality, and the most complete after-sales service.
Customer satisfaction
We are committed to delivering high quality services that exceed our clients' expectations. We strive to ensure that our clients are satisfied with our services and work closely with them to ensure their needs are met.
Types Of Ampoule Filling And Sealing Machine
This machine can fill and seal ampoules automatically without any human intervention. It has a high-speed production capacity and is suitable for large-scale production.
This machine requires some manual intervention in the filling and sealing process. It is suitable for medium-scale production and can handle up to 120 ampoules per minute.
This machine has a rotating carousel that can fill and seal multiple ampoules simultaneously. It has a high-speed production capacity and is suitable for large-scale production.
This machine has a linear design and can handle up to 60 ampoules per minute. It is suitable for small-scale production and has a compact design.
This machine can fill and seal four ampoules at a time, increasing production efficiency. It is suitable for medium-scale production and has a high-speed production capacity.
This machine can fill and seal eight ampoules at a time, increasing production efficiency and speed. It is suitable for large-scale production and has a high-speed production capacity.
How Ampoule Filling and Sealing Machine Works
Ampoule Filling and Sealing Machines are built on the principle based on slant traveling of ampoules when it is filled and sealed. At the same time, other things are taken care of by this equipment like neck dimensions of containers, its thickness and oval form.
Filling Materials
Machine performs filling sealing for wide range of glass ampoules. This device is fully functional in carrying out the filling procedure of liquid in different volumes. Moreover, both air sensitive reagents and injectable pharmaceutical materials are used to fill the ampoules through this. The machine is technologically advanced to such an extent that these environmentally sensitive liquid filled and sealed as soon as they are filled to avoid contamination.
Operating Procedure
The containers are first, sterilized and put in the tray. After that, this tray is directly loaded into slant hopper of unit. Now the machine starts to process, while synchronized start wheels start to deliver one at a time moving in the rack in single, twos, fours or sixes.
The rack stops sequentially and during this period, its every single procedural process is carried out like pre-gassing, filling, post-gassing, pre-heating and finally sealing it out. All the sealed ones are then, collected on tray for collection without manual touching.
Application Of Ampoule Filling And Sealing Machine
Pharmaceutical Industry
Pharmaceutical grade ampoules are one of the most widely accepted and used ampoules of all. The capability of the ampoules to protect the medical constituents of the ampoule from external factors and corrosion makes the ampoules an ideal choice, and the Pharmaceutical Ampoule Filling Machine are the best fit for the particular task.
Food industry
The food industry is the one that is always on the rise, and the number of liquid contents which can use the automatic filling to speed up the process of storage and avoid the risk of spilling and wastage of materials can be easily achieved with the ampoule, container filling machines.
Cosmetic Industry
The cosmetic industry has a vivid range of products and different variants of the same outcome in colours, fragrances and more. With a more significant number of products and the requirement in the market in bulks, the ampoule filling and sealing machine help the manufacturers fill and get the products ready in quantities and at a good space to keep up with the inventory demands.
Chemical Industry
The chemical industry relies heavily on ampoule filling and sealing machine as most chemical manufacturers and distributors use automatic filling and sealing machines to fill their products in containers. The main reason why these machines are prefered in the process is the chemicals can be hazardous and may cause injuries to the workers. The safety of the workers is ensured during the filling and transportation of the chemicals.
Technical Specification Of Ampoule Filling And Sealing Machine
|
Model |
AFS-1 |
AFS-2 |
AFS-4 |
AFS-8 |
|
No. of Head |
Single |
Two |
Four |
Eight |
|
Syringes |
One |
Double |
Four |
Eight |
|
Ampoule Sizes |
1 ml to 30 ml |
1 ml to 30 ml |
1 ml to 10 ml |
1 ml to 20 ml |
|
Filling Speed |
Up to 25 ampoules/minute |
Up to 50 ampoules/minute |
Up to 100 ampoules/minute |
Up to 200 ampoules/minute |
|
Filling Precision |
± 1% |
± 1% |
± 1% |
± 1% |
|
Filling Pump |
Piston Pump |
Piston Pump |
Piston Pump |
Piston Pump |
|
Burner Gas |
LPG & Oxygen (O₂) |
LPG & Oxygen (O₂) |
LPG & Oxygen (O₂) |
LPG & Oxygen (O₂) |
|
Nitrogen Arrangement |
Before & After Filling |
Before & After Filling |
Before & After Filling |
Before & After Filling |
|
Number of Fill Nozzles |
One |
Two |
Four |
Eight |
|
Number of Nitrogen Nozzles |
Two |
Four |
Eight |
Sixteen |
|
Number of Sealing Burners |
Two |
Four |
Eight |
Sixteen |
|
Power Required |
0.5 H.P. |
1 H.P. |
1 H.P. |
2 H.P. |
|
Power Voltage |
230 Volts, Single Phase, 50 Hertz, 4 Wire System |
230 Volts, Single Phase, 50 Hertz, 4 Wire System |
230 Volts, Single Phase, 50 Hertz, 4 Wire System |
230 Volts, Single Phase, 50 Hertz, 4 Wire System |
|
Contact Parts |
Made from Stainless Steel 316L |
Made from Stainless Steel 316L |
Made from Stainless Steel 316L |
Made from Stainless Steel 316L |
|
Overall Dimension |
915mm (L) x 610mm (W) x 965mm (H) approx. |
915mm (L) x 760mm (W) x 965mm (H) approx. |
1200mm (L) x 1070mm (W) x 965mm (H) approx. |
2200mm (L) x 1400mm (W) x 1100mm (H) approx. |
|
|
|
|
|
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Parts Of An Ampoule Filling And Sealing Machine
Filling source
This is where the liquid is fed. It acts as the reservoir tank for the whole filling process and can be refilled when the liquid is depleted
Pedal switch
Adjustable for auto mode operation of the machine depending on the user preference.
Conveyor belt
This conveys the ampoule bottles from the filling station to the receiving station.
Rotary pumps
To ensure that the right pressure is within the ampoule bottle.
Stainless steel belt
This is the part where loading of the ampoules takes place and receives the sealed ampoules.
Volume adjustable wheel
It is used to adjust the volume of the liquid that is fed into the ampoule bottles.
Sensor of volume
Responds to the changes in the volume as adjusted by the adjustable volume wheel.
Plunger
Used to squeeze or push the liquid into the ampoule bottle.
Needle bevel
To allow passage of the liquid into the ampoule bottle.
Exhaust fume excavator
To channel out the fumes produced during the ampoule sealing process.
How to Troubleshoot Ampoule Filling and Sealing Machine
This may not be the wish of any user of this machine.
But in the course of production, some ampoules may not be completely sealed.
Solution: These can be solved by adjusting the sealing system in an appropriate angle to ensure efficiency in the sealing system.
No worry again, sometimes the conveyor may fail to pass the bottles at the right time for filling.
This often affects the sealing system.
Solution: This is automatically solved by adjusting the system. But again remember that any ampoule filling and sealing machine works under the principle of "no ampoule no filling function."
Well, sometimes the fills may not level. This might be quite frustrating.
Then what do you do?
Solution: You need to ensure that the ampoule filling and sealing machine is on a flat floor meant for production.
Again, during the changeover from one ampoule to another, some ampoules may not be in a filling line.
Solution: Ensure that there are correct spacers along the production line.
The operators should ensure that they do a visual inspection and monitoring the ampoules as they are filled and sealed.
This may fail to work for some reason but often due to mechanical problems.
What may happen is that the airlines that have the connection to the head dive may have a leak or sometimes may become disconnected.
Solution: Ensure that you check all airlines as well as the air compressor to ensure all connections are secure and that compressed air is supplied to the machine.
Maintenance Tips for Ampoule Filling and Sealing Machine
Regular cleaning
Proper cleaning is crucial to avoid any contamination of the ampoules. Clean the machine regularly after every use to remove any residue left behind in the tubes and needles.
Lubrication
Regular lubrication of the vital parts and components of the machine is critical to ensure smooth operation and prevent wear and tear.
Inspection of parts
Components like O-rings, needles, and tube holders should be inspected for any signs of wear and tear and replaced if necessary.
Calibration
Regular calibration of the machine is necessary to maintain the required filling and sealing accuracy.
Operator training
Adequately trained operators can ensure that the machine is used correctly, reducing the likelihood of any errors or accidents.
Regular maintenance checks
Regularly check the machine for any issues like leaks, electrical problems, and wear and tear of essential parts.
Use high-quality consumables
Using high-quality consumables like ampoules and sealing materials will result in better-quality products and prevent any machine malfunctions.
Keep the machine dry
Keep the machine away from moisture and water to prevent any rust or corrosion of vital parts.
Replace worn-out parts
Replace the worn-out parts regularly to avoid any machine breakdowns.
Follow manufacturer guidelines
Always follow manufacturer guidelines and instructions to ensure optimal machine performance and longevity.
Our Factory
Shanghai Marya Pharmaceutical Engineering and Project Co., Ltd. was founded in 2014 in Shanghai, China, is a total solution provider specializing in engineering design, clean room engineering, pharmaceutical engineering, pharmaceutical equipment, project management and verification and other technical services. We have three factories and a number of experts and technicians who have been engaged in pharmaceutical and medical industries for more than 20 years. Worriless and relieved solution for customer is our value proposition, we are consistently committed to helping clients to design and build clean workshops, pharmaceutical turnkey solutions.
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