Solution Of Purified Water System Of Biological Medicine

I. Introduction:

The whole set of purified water system of biological medicine is made of stainless steel and its control system employs full automatic PLC+ touch screen, featuring stable running, beautiful appearance and simple and convenient operation. The main materials are those recognized by the industry, with high quality and design as per configuration. In addition, purified water insulation tank is provided.

Requirements on water for biological medicine production are more stringent. To ensure water safety in biological medicine production, the whole system is made of stainless steel and the water outlet is equipped with a sterilization device. Reverse osmosis, EDI and other technologies are adopted and targeted complete highly purified water processing process is designed proceeding from characteristics of purified water in the pharmaceutical industry and based on different customers' requirements on purified water, thus meeting water demand for purified water preparation and iv infusion preparation in pharmaceutical factories and hospitals.

Processes of solutions for purified water preparation in pharmaceutical industry is mainly divided into the following:

1、Raw water →booster pump of raw water →quartz sand filter →activated carbon filter →water demineralizer (optional) →cartridge filter→ primary reverse osmosis equipment→ sterile pure water tank →pure water booster pump→ ultraviolet sterilizer→ microfilter→ EDI system→ sterile purified water tank→ ozone sterilizer→ purified water booster pump→ ozone sterilizer→ ultraviolet sterilizer→ microfilter →purified water user point

2、Raw water →booster pump of raw water →quartz sand filter →activated carbon filter →water demineralizer (optional) →cartridge filter→ primary reverse osmosis→ pure water tank →pure water booster pump→ secondary reverse osmosis →sterile purified water tank→ ozone sterilizer→ purified water booster pump→ ozone sterilizer→ ultraviolet sterilizer→ microfilter →purified water user point

3、Raw water →booster pump of raw water →quartz sand filter →activated carbon filter →water demineralizer (optional) →cartridge filter→ primary reverse osmosis equipment→ pure water tank →pure water booster pump→ secondary reverse osmosis equipment→ sterile pure water tank →pure water booster pump→ ultraviolet sterilizer→ microfilter→ EDI system→ sterile purified water tank→ ozone sterilizer→ purified water booster pump→ ozone sterilizer→ ultraviolet sterilizer→ microfilter →purified water user point (this process is recommended when the conductivity of raw water is greater than 1000μS.)

II. Performance characteristics:

1. Water produced complies with standards for purified water specified in 2010 Pharmacopeia and GMP, FDA and other related standards;

2. Imported instruments are used to realize accurate and continuous analysis and display of water quality. When water quality is unqualified, an alarm will be given and automatic handling will be performed;

3. Imported pump, reverse osmosis membrane and other quality components are used;

4. The whole system employs full automatic control with simple and easy operation;

5. The whole system is made of stainless steel and purified water production pipeline is made of 316L stainless steel;

6. The purified water system is equipped with a mirror finished raw water tank and intermediate water tank to prevent influence on equipment from unstable tap water pressure;

7. All pipelines are welded with both-side formation and be subjected to passivation;

8. Purified water tank is provided with electronic level gauge, rotary spray cleaning device and air-breathing apparatus;

9. Ozone sterilization and ultraviolet sterilization system as well as terminal microfiltration apparatus are provided;

10. Pure steam generator is provided to realize instantaneous sterilization of pipelines by pure steam (optional);

11. Water demineralizer is provided to ensure no influence to stable operation of RO system and EID system from hardness (optional);

12. PH adjustment and on-line detection system is provided to adjust PH value to prevent influence of CO2 to quality of water produced;

13. Ultra-low-pressure reverse osmosis is adopted to realize high desalinization ratio, long service life, stable operation and reduction of energy consumption by 20%;

14. Two-stage reverse osmosis system of purified water equipment adopts full automatic control mode, of which main elements are those imported with high stability and simple and convenient operation;

15. EDI system employs a constant pressure regulation system to ensure stable water quality;

16. Siemens Ionpure series CEDI membrane stack is used with stable performance and long service life. Besides, stable water quality is guaranteed through professional technology in case of short time or long time shut-down of EDI system;

17. EDI flow meter is an imported flow meter with magnetic induction float, to prevent water production without concentrated water due to blocking of concentrated water channel or failure of other devices, thus damaging membrane stack;

18. A purified water convey system is provided;

19. The control system employs PLC+ touch screen automatic control mode, of which main elements are those imported with high stability and simple and convenient operation;

20. Main materials are of quality brand in the industry which are designed as per configuration to ensure quality.